Mahesh is an ambassador for about a dozen South Indian brands. In 2007, he signed a five-year endorsement deal with the cola company Thums Up to replace Chiranjeevi as its brand ambassador in Andhra Pradesh. He endorsed brands such as UniverCell Mobile Store, Navratna Oil, Amrutanjan, Provogue, ITC Vivel, Jos Alukkas, Idea Cellular, Santoor Soap, South India Shopping Mall, Royal Stag, Rainbow Hospitals, TVS Motor Company, Mahindra Tractors, Paragon footwear, and Tata Sky in South India. He was signed as the brand ambassador of Intex Mobiles in August 2015 for one year. In 2012, he replaced Akshay Kumar as the national brand ambassador for Thums Up across India. He also promotes the real estate firm Ramakrishna Venuzia. Mahesh commands a figure of ₹ 25–30 million per endorsement per annum, thus earning around ₹ 300 million per annum as a brand ambassador. In 2016, he was signed as the brand ambassador of YuppTV and AbhiBus. In February 2018 he was signed as the brand ambassador for Protinex. Some of the other brands he endorses, or had endorsed previously, include Chennai Silks, Sai Surya Developers, Close-Up, Gold Winner, Denver Deodorant, Lloyd A/C, and Flipkart. Overall, Mahesh has endorsed 28 brands thus far.
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